Panel 02 / NAD-BLU
CLIA-certified Lab
Sirtuin ActivityPARP PathwayMitochondrial FunctionDNA RepairOxidative Stress
Energy & Mitochondrial Function
This panel highlights NAD-related biomarkers commonly referenced in discussions of cellular energy production and mitochondrial activity. Results are presented in a standardized laboratory format to help organize these markers for baseline reference and comparison alongside other longevity-focused data.
Research Evidence
NAD⁺ is the essential substrate for sirtuins — the enzymes that regulate energy metabolism, stress resistance, and DNA repair
NAD⁺ deficiency is directly linked to age-related mitochondrial dysfunction across brain, liver, muscle, and skin tissue
NADH elevation is a validated marker of mitochondrial reductive stress — measurable before symptoms appear
Research Basis
NAD⁺ levels are tightly controlled to ensure maintenance of cellular health. NAD⁺ and NADH ratios are particularly important for energy generation, metabolic homeostasis, mitochondrial function, and DNA repair.
Nature npj Metabolic Health and Disease, 2025 · doi:10.1038/s44324-025-00067-0